Sutent - Newsfeeds

Pipeline Review: Bristol-Myers Squibb's 5 Keys to Success
It's the same strategy that Pfizer followed for Sutent and that Bayer and Onyx Pharmaceuticals followed for Nexavar. All three drugs inhibit growth factor receptors required for blood vessel growth. No blood,
Chemo for Cancer Patients With HIV May Change
Treatments that Work While they specifically tested a new chemotherapy called Sutent, the study applies to about half of all cancer drugs that use the same enzymes. ?Patients treated with one type of drug cocktail to ...
Sector Wrap: Technology, Pharmaceuticals
Pfizer (NYSE:PFE) said that its phase 3 trial of Sutent to treat non-small cell lung cancer failed to meet its primary endpoint. Sutent did not show increased overall survival when used in combination with Tarceva ...
Pfizer Failure Clears Way for Small Biotech ArQule
The Big Pharma announced Monday night that its cancer drug Sutent didn't show statistically significant improvement of overall survival in second- and third-line non-small cell lung cancer patients -- the primary ...
Pivotal Phase III Trial of Novartis Drug Afinitor® Met Primary Endpoint in Study of Patients With ...
... the trade name Afinitor® (everolimus) tablets for the treatment of patients with advanced renal cell carcinoma (RCC) after failure of treatment with sunitinib or sorafenib. Pancreatic NET can grow aggressively and ...
Bevacizumab Linked to Increased Risk for High-Grade Proteinuria and Nephrotic Syndrome
... class effect of vascular endothelial growth factor (VEGF) inhibitors and that "other VEGF-signaling blockers including axitinib, VEGF Trap, sorafenib, and sunitinib have also been associated with severe proteinuria ...
Cancer patients 'can't wait a year for drugs cash'
The 37-year-old had fought against a decision by health chiefs at NHS West Kent not to fund Sunitinib. They claimed there was not enough evidence to prove the drug, which is used for kidney cancer, would work on her ...
Consortium Seeks Best Treatment for HIV-positive Cancer Patients
Washington, DC – Preliminary findings from a unique study with sunitinib suggest that it might be possible to tweak the dosage of chemotherapy drugs used to treat HIV-positive cancer patients to achieve therapeutic ...
Argos Therapeutics Presents Positive Phase 2 Data for Arcelis(TM) Dendritic Cell-based...
... positive interim data from a Phase 2 trial that evaluated the clinical activity, safety and immune response of AGS-003 treatment, given in combination with sunitinib, in patients with newly diagnosed advanced renal ...
Chemotherapy drug sunitinib promising for HIV-positive cancer patients
For reasons that are unclear, cancers that are unrelated to HIV infection are growing at an alarming rate in these patients, compared to the general HIV-negative population, he says. These non-AIDS-defining cancers are ...
Argos Therapeutics Presents Positive Phase 2 Data for Arcelis Dendritic Cell-based Immunotherapy in ...
... positive interim data from a Phase 2 trial that evaluated the clinical activity, safety and immune response of AGS-003 treatment, given in combination with sunitinib, in patients with newly diagnosed advanced renal ...
Kidney Damage Affirmed with Biologic-Chemo Combo
... s group noted, saying it may be a class effect given elevated severe proteinuria rates seen in trials with axitinib, sorafenib (Nexavar), and sunitinib (Sutent). The authors noted several limitations including the ...
Cancer Meeting's Winners And Losers
Pfizer had a success this meeting with a lung cancer drug for patients with a rare genetic mutation, but big studies of its Sutent in breast cancer failed. The hottest new area this year was in drugs that boost the ...
Seeking The Best Treatment For HIV-Positive Cancer Patients
This study is testing the safety of the chemotherapy drug sunitinib ( Sutent ) and has enrolled patients into two groups of HIV patients - group 1: those using non-nuceleotide analog reverse transcription inhibitors ...
How Pfizer's Pain Could Be Your Gain
In March, The New York-based pharma giant announced that two late-stage breast cancer trials of its drug Sutent didn't meet the primary endpoints. On top of the Sutent flop, the company also announced that it’s ...
Pfizer Drug Targets Gene Flaw to Shrink Lung Tumors (Update1)
That same month, the company said Sutent, approved for kidney and stomach cancers, failed in two studies to shrink tumors of the breast, and its experimental drug figitumumab didn’t help lung cancer patients.
What Happened at ASCO Over the Weekend
And Pfizer’s Sutent, already shown to work in kidney cancer, does not produce similar beneficial effects in breast cancer patients. There was some good news in the breast cancer field, however, with Eisai’s ...
People on HIV Meds Might Need Different Chemo Doses for Cancer
A study in progress suggests that the dose of Sutent (sunitinib)—a chemotherapy—might need to be adjusted up or down depending on the antiretroviral (ARV) treatment a person is taking. The authors of the study, to be ...
HORMONE REFRACTORY PROSTATE CANCER: NEW STUDIES IN ...
The third trial at the Medical University of Vienna will test the combination of docetaxel with the tyrosine kinase inhibitor sunitinib. As part of the trial, the researchers will examine biomarkers in the patients' blood that will yield information ...
Life-saving cancer drugs still not available on NHS
They include Hycamtin (topotecan), for lung and cervical cancer, Mabthera (rituximab) for chronic lymphocytic leukaemia and Sutent (sunitinib) for stomach tumours. Sir Andrew Dillon, chief executive of Nice, insisted however that partial ...
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